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Vildagliptin

Vildagliptin

Synonym

(S)-1-[N-(3-hydroxy-1-adamantyl)glycyl]pyrrolidine

-2-carbonitrile

CAS #

274901-16-5

Molecular Formula

C17H25N3O2

Molecular Weight

303.40

Structure

CAS 274901-16-5

Product Introduction

Vildagliptin (previously identified as LAF237, trade names Zomelis, Galvus, cas 274901-16-5) is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin (cas 274901-16-5) inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas.Vildagliptin (cas 274901-16-5) has been shown to reduce hyperglycemia in type 2 diabetes mellitus.