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Home>Products & Services> (1R)-(S)-Pinanediol 1-ammonium trifluoroacetate-3-methylbutane-1-boronate

(1R)-(S)-Pinanediol 1-ammonium trifluoroacetate-3-methylbutane-1-boronate

(1R)-(S)-Pinanediol 1-ammonium trifluoroacetate-3-methylbutane-1-boronate

Synonym

(R)-BoroLeu-(+)-Pinanediol-CF3CO2H

CAS #

179324-87-9

Molecular Formula

C17H29BF3NO4

Molecular Weight

379.22

Structure

Cas 179324-87-9

It (cas 179324-87-9) is an intermediate of bortezomib. Bortezomib marketed as Velcade by Millennium Pharmaceuticals) is the first therapeutic proteasome inhibitor to be tested in humans. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.