banner
Home>Products & Services> Bortezomib Pinanediol Ester

Bortezomib Pinanediol Ester

Bortezomib Pinanediol Ester

Synonym

(1S,2S,3R,5S)-Pinanediol N-(2-pyrazinecarbony1)-L-phenylalanine-L-leucine boronate

CAS #

205393-22-2

Molecular Formula

C29H39BN4O4

Molecular Weight

518.46

Structure

Cas 179324-87-9

Bortezomib-Pinanediol (cas 205393-22-2) is an intermediate of bortezomib. Bortezomib marketed as Velcade by Millennium Pharmaceuticals) is the first therapeutic proteasome inhibitor to be tested in humans. It is approved in the U.S. for treating relapsed multiple myeloma[1] and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.